LY294002 – PI3K Inhibitor | AbMole

LY294002 is a potent, cell-permeable phosphoinositide 3-kinase (PI3K) inhibitor, offered by AbMole, widely used in cancer biology, signal transduction, and cell survival studies. LY294002 blocks the PI3K/AKT/mTOR pathway, a key regulator of cell proliferation, metabolism, and apoptosis.

By inhibiting PI3K activity, LY294002 is frequently used in preclinical models to assess tumor sensitivity to pathway suppression and to explore combination treatment strategies.

Applications

•     PI3K/AKT/mTOR signaling pathway inhibition
•     Cancer and tumor progression studies
•     Apoptosis and autophagy research
•     Metabolic regulation and insulin signaling
•     Investigating chemosensitization and resistance mechanisms

Product Highlights

•     Chemical Name: LY294002
•     CAS Number: 154447-36-6
•     Molecular Formula: C19H17ClN2O3
•     Purity: ≥98% (HPLC)
•     Soluble in DMSO
•     Manufactured by AbMole BioScience

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