Magnetic beads for targeted DNA/RNA capture

Targeted capture of DNA and RNA 

Magnetic beads based on a novel variety of magnetic nanoparticles, which can capture any given DNA/RNA molecule in a sequence-specific manner.

Particularly efficient for epigenetics studies, interactome analysis, and targeted sequencing with 2nd and 3rd generation sequencing platforms.

DNA probes covalently attached to the beads:

The beads are produced through a novel approach of direct synthesis of DNA capture probes on the surface of functionalized magnetic nanoparticles. The synthesis reaction produces a high number of oligonucleotide chains, which are covalently attached to the surface of the particles through their 5’ ends.

Bind to multiple regions of a target:

The beads developed for the capture of a specific sequence carry an array of different probe sequences which target multiple regions of the same target DNA or RNA molecule. The fact that those unique probes are clustered together in close proximity to one another allows them to act in synergy in binding the target (hybridization of a single probe brings the target within close proximity to other capture probes)

Off the shelf kits:

MS2 aptamere, Cassava brown streak virus (CBSV), Mus musculus cdr1as, Chikungunya virus, Deformed wing virus (DWV), Dengue virus, Arabidopsis thaliana DOG1, Ebola, East African cassava mosaic virus (EACMV), Mus musculus GAPDH, Homo sapiens GAPDH, Hepatitis C, Hepatitis E, HIV, Influenza viruses, Homo sapiens MALAT1, MERS-CoV, MS2, Homo sapiens Myotic dystrphy related CUG repeat, SARS / SARS-CoV-2, Ugandan cassava brown streak virus (UCBSV), Yellow fever virus, Zika virus.

Contact us for Custom target RNA or DNA Seq MagIC Beads.