3-Methyladenine – Autophagy Inhibitor | AbMole

3-Methyladenine (3-MA) is a widely used autophagy inhibitor, offered by AbMole, that selectively inhibits class III PI3K (phosphoinositide 3-kinase) activity. This compound is instrumental in studying autophagic pathways, blocking autophagosome formation, and modulating cell survival and metabolism.

Inhibition of PI3K by 3-MA allows researchers to dissect the role of macroautophagy in various physiological and pathological processes, including cancer, neurodegeneration, and infection.

Applications

•     Inhibition of autophagy
•     Class III PI3K pathway studies
•     Cell survival and death signaling
•     Neurodegenerative disease models
•     Cancer research and metabolic regulation

Product Highlights

•     Chemical Name: 3-Methyladenine (3-MA)
•     CAS Number: 5142-23-4
•     Molecular Formula: C6H7N5
•     Purity: ≥98% by HPLC
•     Soluble in DMSO and water
•     Manufactured by AbMole BioScience

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