ArcticZymes IsoPol™ DNA Polymerases – For Isothermal Amplification

ArcticZymes IsoPol™ DNA Polymerases are a family of engineered, high-efficiency polymerases designed specifically for isothermal amplification techniques.

Whether you're performing LAMP (Loop-mediated Isothermal Amplification), RCA (Rolling Circle Amplification), SDA (Strand Displacement Amplification), or other non-cycling DNA synthesis applications, the IsoPol™ range provides robust and consistent performance.

All variants are available on this page and are optimized for different fidelity, speed, and buffer conditions to meet diverse assay needs.

Description: 

IsoPol™ DNA Polymerase is active at ambient temperatures.

It exhibits 5’-3’ polymerase activity and lacks 3’-5’ exonuclease activity. The 5’-3’ exonuclease domain is truncated, thus the enzyme also lacks 5’-3’ exonuclease activity. IsoPol™ DNA Polymerase has excellent processivity and strong stand-displacement activity.

In addition, it can be heat inactivated at temperatures above 50°C.

• Recombinant IsoPol™ DNA Polymerases from ArcticZymes
• Specifically engineered for isothermal amplification workflows
• Ideal for LAMP, RCA, SDA, and other non-thermal cycling methods
• Available in multiple variants with optimized fidelity and activity
• Compatible with diagnostics, molecular biology, and field-based testing
• Reliable performance in challenging and low-resource conditions

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