Antibody labeling with only 30 seconds hands-on time

Two Steps, 30 Seconds Hands-on Time, 100% Sample Recovery

The oYo-Link® Conjugation Technology can be used to site-specifically and covalently label the Fc region of almost any “off-the-shelf” antibody with biotin, click chemistry tags (e.g. azide, DBCO), epitope tags, enzymes (e.g. MNase), HyperBright™ fluorescent labels, oligonucleotides, and more.

oYo-Link reagents consist of low molecular weight (~8 kDa), high-affinity antibody-binding domains that possess a photo-crosslinker within their Fc-binding site. Upon illumination with non-damaging Black-light, oYo-Link forms a covalent bond with the antibody.

Oligonucleotide Conjugations

• Oligo Custom

Click-Chemistry & Chemical Conjugations

• Azide
• Thiol
• DBCO
• Tetrazine

Surface Immobilization

• Single-Biotin
• His12 Tag

Antibody-Drug Conjugation

• Monomethyl Auristatin E. (VcMMAE)
• DM1
• Monomethyl Auristatin F. (VcMMAF)