MALBAC Single Cell WGA Kit

Whole Genome Amplification for Single Cell(s), Picogram to Sub-nanogram Quantities of gDNA

Features:

• Quasi-linear amplification with the least amplification bias
• High sequencing coverage and uniformity
• Low allele dropout rate
• Single tube sample preparation in 4 hours
• Suitable for single-cell CNV/SNV analysis, PGS/PGD, and CTC studies

Overview

Based on the patented MALBAC™ technology from Harvard University, MALBAC™ Single Cell WGA kit provides rapid, reliable and reproducible whole genome amplification of single cell(s) or picogram to sub-nanogram quantities of gDNA to produce 2-4 micrograms of amplified products in about 4 hours.

The kit is able to achieve consistent amplification efficiency in both AT- and GC-rich regions for most cell types, such as blastomere, polar body, sperm and various cell lines. More than 90% of genomic loci can be amplified and analyzed using different platforms, such as real-time PCR and next-generation sequencing.

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